Addressing ASD symptoms via supplementation with Speak® in combination with Hericor-MRL
Severe and moderate Autistic Spectrum Disorder (ASD) patients exhibit an under-connectivity between sensory cortices and association cortices leading to a failure to assimilate sensory information into a working environmental context. Additionally, ASD patients have a lack of connectivity of associative cortices to the frontal cortex.
One option on addressing the symptoms exhibited by ASD patients in order to improve the quality of life for moderate and severe ASD patients and their care givers is combining paediatrician formulated NourishLife Speak® – which provides 7 nutrients in precise doses and ratios for children with special nutritional requirements – with Hericor-MRL supplementation that supports the repair of intestinal “villi”, helping effective nutrients absorption in the small intestine
Speak® is a proven supplement in a capsule form containing pharmaceutical grade Omega-3 with GLA and two specific types of Vitamins E and Vitamin K.
Speak® supplementation is gradually increased until a demonstrative change in behaviour or speech pattern is developed.
Hericor-MRL supplementation addresses the gastrointestinal discomfort. In vitro studies demonstrate that constituents within Hericor-MRL have prebiotic activity and animal studies demonstrate the same constituents also increase Lipoxin A4 (leading to a reduction in neuroinflammation) in rats and increase neurogenic reserve in mice.
Core CNS Symptoms in Moderate and Severe ASD Patients*
- Impaired social communication and interaction.
- Restricted, stereotyped and repetitive patterns of behaviour and interests.
- Other disorders of the CNS:
- motor deficits
- speech disorders
- sensory impairments
- anxiety and phobias
- behavioural problems
- sleep disorders
- delayed intellectual development
- obsessive-compulsive disorder
These ASD CNS (central nervous system) symptoms are caused by:
- Impaired neurogenesis and apoptosis.
- Impaired synaptogenesis and synaptic pruning.
- Imbalanced excitatory-inhibition system.
In the first week, start the administration of 4g/day of Hericor-MRL (2g with breakfast and 2g with lunch) followed for 60 days. The Hericor-MRL powder can be added to non-citric yoghurt or to the meal.
After the 60 day supplementation period the use of of Hericor-MRL should cease. Subsequent use should only be when gastrointestinal discomfort return.
In the second week begin Speak® supplementation with 1 capsule daily with meals for two weeks and then increase gradually by an additional capsule for another two weeks and then continue until there is a change in behaviour (i.e. calm or verbal expression).
If after a change in behaviour, there is no additional improvement with a higher daily dosage, then return to previous supplementation level of the previous two weeks and maintain.
It is recommended that Speak® be taken for at least a minimum of 4 months.
Typical supplementation for small children (under 65 Kg) is 2 to 4 capsules per day (3,0 to 6,0ml per day). For older children (65 Kg+) 4 to 6 capsules per day (6,0 ml to 9,0 ml).
When starting the protocol, there may be a change in bowel movements with loose stools and a “runny tummy”. This condition should clear within 5 to 7 days. If persists after five days, discontinue use of product as this could cause dehydration.
*Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis. Rossignol, Frye Mol Psychiatry. 2012 Mar;17(3):290-314. doi: 10.1038/mp.2010.136. Epub 2011 Jan 25.